Our Research
The Miller Lab in the Center for Public Health Genomics at the University of Virginia focuses on integrating large-scale human genetics and genomics datasets with clinically relevant functional models. We employ an array of bioinformatics approaches and phenotypic screens using both genetic and drug perturbations to investigate causal mechanisms at candidate loci.
Our primary goals are to:
- Understand fundamental vascular biology and disease regulatory mechanisms.
- Identify new targets or risk factors for complex cardiovascular diseases.
- Investigate role of candidate genes on vascular wall processes using preclinical and repositioned therapeutics.
Recent Projects
News
Congratulation to Dr. Yipei Song !!
Yipei successfully defended her PhD on this September 18th, 2025
John Stubb and Maria Murach at the UVA Biomedical Sciences diploma presentation and hooding ceremony
During the “Finals Weekend” on ground at UVA, John Stubb and Maria Murach received their diploma during the formal graduation ceremony
The Miller Lab is in London to present their work at the Comet Leducq network Meeting
https://www.linkedin.com/company/comet-leducq-network/
Shay showcases their work at the PacBio Launch Party
Shay got to present their work on Isoform Drivers of Atherosclerotic Smooth Muscle Cell Changes.
The Miller lab is well represented at the Department for Genome Science retreat
Miller lab at 1st annual DGS retreat with Jose and famous alum Chani Hodonsky
Congratulations To Jose and Clint for their publication in ATVB !
Single-cell RNA sequencing reveals sex differences in the subcellular composition and associated gene-regulatory network activity of human carotid plaques
Congratulations to Jose, recipient of the 2025 Biomedical Sciences (BIMS) Outstanding Graduate Student Award
https://med.virginia.edu/bims/2025-biomedical-sciences-bims-outstanding-graduate-student-awardees/