Our Research

The Miller Lab in the Center for Public Health Genomics at the University of Virginia focuses on integrating large-scale human genetics and genomics datasets with clinically relevant functional models. We employ an array of bioinformatics approaches and phenotypic screens using both genetic and drug perturbations to investigate causal mechanisms at candidate loci.

Our primary goals are to:

  • Understand fundamental vascular biology and disease regulatory mechanisms.
  • Identify new targets or risk factors for complex cardiovascular diseases.
  • Investigate role of candidate genes on vascular wall processes using preclinical and repositioned therapeutics.
Recent Projects
News

The Center for Public Health Genomics transition to the Department of Genome Sciences (DGS)

Announcing the New Department of Genome Sciences

Congratulations to Clint and the lab for their award

Clint Miller, PhD, Awarded $2.8 Million NHLB Grant to Research Coronary Artery Disease

Aditi and Ivory represent the lab at the Undergrad Research Symposium

Shay Iyer receive their White Coat !

BIMS Students Receive Their First Lab Coats

Congratulations to Dr. Miller to make it to the CEO’s list !

Chani Hodonsky’s paper is featured in UVAHealth Newsroom

UVA Getting to Heart of Coronary Artery Disease

Congrats to Chani Hodonsky on her first author manuscript published in Cell Genomics!

Multi-ancestry genetic analysis of gene regulation in coronary arteries prioritizes disease risk loci

Jose V. Mosquera’s paper is featured in UVAHealth Newsroom

‘Atherosclerosis Atlas’ Sheds Light on Heart Attacks, Strokes

Congrats to Jose Verdezoto Mosquera on his first author manuscript published in Cell Report!

Integrative single-cell meta-analysis reveals disease-relevant vascular cell states and markers in human atherosclerosis

Dr. Miller and collaborators’s paper is featured in UVAHealth Newsroom

Gene Discoveries Could Help Prevent Coronary Artery Disease