Our Research

The Miller Lab in the Center for Public Health Genomics at the University of Virginia focuses on integrating large-scale human genetics and genomics datasets with clinically relevant functional models. We employ an array of bioinformatics approaches and phenotypic screens using both genetic and drug perturbations to investigate causal mechanisms at candidate loci.

Our primary goals are to:

• Understand fundamental vascular biology and disease regulatory mechanisms.
• Identify new targets or risk factors for complex cardiovascular diseases.
• Investigate role of candidate genes on vascular wall processes using preclinical and repositioned therapeutics.